Remco Evenepoel enters the stage as the primary favorite for the sole individual time trial in this year's Tour de France.
The 26.1km route starts from Évian-les-Bains with an immediate uphill segment.
Riders must tackle the category two Côte de Larringes, which spans 9.7km at an average gradient of 4.3%.
Following the climb, the course presents a technical descent leading toward the Lake Geneva coastline in Thonon-les-Bains.
Standings Shift After Vingegaard's Withdrawal
The overall standings took a dramatic turn following the withdrawal of Jonas Vingegaard.
The Danish rider crashed out a day after experiencing a 2 a. m.
doping control disruption, solidly establishing Tadej Pogacar in a dominant position.
While Evenepoel aims to trim Pogacar's five-minute lead by securing a time trial victory, Pogacar himself remains a strong contender to claim the stage win given his overall capabilities.
Other competitors pushing for top results include the Netcompany-Ineos duo Filippo Ganna and Josh Tarling, along with Lidl-Trek rider Juan Ayuso as a dark horse candidate.
Focus also shifts to the intense podium rivalry and the battle for the young rider's jersey between Isaac del Toro and Paul Seixas.
Although Seixas possesses better capabilities against the clock, fatigue from two weeks of continuous racing remains a factor.