Remco Evenepoel enters the stage as the primary favorite for the sole individual time trial in this year's Tour de France.
The 26.1km route starts from Évian-les-Bains with an immediate uphill segment.
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Riders must tackle the category two Côte de Larringes, which spans 9.7km at an average gradient of 4.3%.
Following the climb, the course presents a technical descent leading toward the Lake Geneva coastline in Thonon-les-Bains.
Standings Shift After Vingegaard's Withdrawal
The overall standings took a dramatic turn following the withdrawal of Jonas Vingegaard.
The Danish rider crashed out a day after experiencing a 2 a. m.
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doping control disruption, solidly establishing Tadej Pogacar in a dominant position.
While Evenepoel aims to trim Pogacar's five-minute lead by securing a time trial victory, Pogacar himself remains a strong contender to claim the stage win given his overall capabilities.
Other competitors pushing for top results include the Netcompany-Ineos duo Filippo Ganna and Josh Tarling, along with Lidl-Trek rider Juan Ayuso as a dark horse candidate.
Focus also shifts to the intense podium rivalry and the battle for the young rider's jersey between Isaac del Toro and Paul Seixas.
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Although Seixas possesses better capabilities against the clock, fatigue from two weeks of continuous racing remains a factor.