The Philadelphia Phillies open a three-game home series against the Cleveland Guardians on Friday, May 22, 2026, at 6:40 p.
m. ET at Citizens Bank Park.
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The matchup features two teams moving in opposite directions. Cleveland enters with a six-game winning streak and a 30-22 record, the best 10-game start in MLB.
The Phillies sit at 25-25 after a series loss to Cincinnati where they managed only 14 hits in three games.
Pitching Matchup
Left-hander Cristopher Sánchez starts for Philadelphia.
He holds a 5-2 record with a 1.82 ERA and has thrown 24 consecutive scoreless innings over his last three starts, including a complete-game shutout against Pittsburgh with a career-high 13 strikeouts and no walks.
Sánchez has an 80-to-14 strikeout-to-walk ratio over 64 1/3 innings this season.
He faces a Cleveland lineup featuring José Ramírez, rookie Chase DeLauter (30 RBIs), and former Phillie Rhys Hoskins.
The Guardians counter with right-hander Gavin Williams, who has a 6-3 record and a 3.67 ERA.
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Williams has struck out 73 batters over 61 1/3 innings in 10 starts.
Key Players
Phillies outfielder Brandon Marsh enters with a . 325 batting average, .
350 on-base percentage, and . 464 slugging percentage.
He has four home runs, 22 RBIs, and 26 runs scored in 177 plate appearances.
Philadelphia welcomes back outfielder Kyle Schwarber, who missed the previous series due to a stomach illness.
During his absence, Alec Bohm hit two home runs against the Reds while shifting to first base defensively.
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The series continues Saturday afternoon with Zack Wheeler facing Slade Cecconi, followed by a Sunday finale between Andrew Painter and Parker Messick.