"I reckon Usyk stops Verhoeven in rounds six or seven," said Darren Barker, British ex-middleweight world champion.
Former champions highlighted the unique nature of the spectacle compared to past crossover events.
"It's a crazy, crazy fight. Probably more crazy than Francis Ngannou against Tyson Fury or Anthony Joshua.
I think Usyk will just have a bit of fun, being the showman that it is.
He could do it early but he wraps it up by the halfway mark," said Anthony Crolla, ex-WBA lightweight title holder.
Elite active fighters expressed complete confidence in the champion's preparation and skill level.
"I know Usyk and I know what level he's on and I think he's up for it.
[and] put on an amazing show," said Terence Crawford, three-weight former undisputed champion.
Promoters acknowledged the physical challenge Verhoeven presents but doubted it would affect the outcome.
"Verhoeven is going to be a handful but unfortunately for him he's fighting one of the best to ever do it.
So I can't see anything else other than an Usyk victory," said Eddie Hearn, promoter.
Commentators suggested the challenger's durable background will prolong the fight past the opening frames.
"I think Usyk will win the fight.
It will be late or on points but if I had choose then I'll probably go with a late stoppage.
Verhoeven will be in the fight early on and he will be dangerous as he can hit very hard.
But Usyk will do what he does - he will work it out and eventually take him apart and stop him late," said Richie Woodhall, ex-WBC super-middleweight champion.
