The 2026 NFL season reaches Week 3 on Sunday, September 27, with divisional rivalries, injury adjustments, and a historic international debut in South America.
The AFC North opens with an undefeated Cincinnati Bengals team visiting the Pittsburgh Steelers at Acrisure Stadium.
Cincinnati improved to 2-0 after wins over Tampa Bay and Houston, powered by a revamped defensive line featuring Dexter Lawrence and Cashius Howell that has recorded eight sacks.
Quarterback Joe Burrow threw two touchdown passes to Ja'Marr Chase in Week 2.
Pittsburgh, meanwhile, looks to bounce back from a loss to New England behind veteran quarterback Aaron Rodgers and a defense averaging 3.5 sacks from T.
J. Watt.
Bills Host Chargers as Chiefs Visit Dolphins
In the AFC East, the 2-0 Buffalo Bills host the Los Angeles Chargers, who are still searching for their first win after opening losses to Arizona and Las Vegas.
Buffalo enters the contest averaging 38.5 points per game under quarterback Josh Allen.
Los Angeles has dealt with offensive line injuries and has managed just 14 points per game.
The Kansas City Chiefs travel to face the 0-2 Miami Dolphins at Hard Rock Stadium as 10.5-point favorites.
Kansas City relies on running back Kenneth Walker and quarterback Patrick Mahomes.
Miami struggles under first-year head coach Jeff Hafley after allowing nine sacks and recording zero through two weeks.
Travel schedules also impact several squads, headlined by the Dallas Cowboys and Baltimore Ravens traveling to Rio de Janeiro, Brazil, for the first-ever NFL Rio Game.
Elsewhere, West Coast teams face early kickoffs on the East Coast as the Seattle Seahawks visit the Washington Commanders, who will start Marcus Mariota in place of the injured Jayden Daniels.
NFL Week 3 highlights feature divisional rivalries, heavy favorites, injuries, and a historic international matchup in Rio de Janeiro.
