The undefeated Buffalo Bills host the Los Angeles Chargers on Sunday, September 27, 2026, at Highmark Stadium in Orchard Park, New York, for their Week 3 matchup broadcast on FOX.
Los Angeles enters the contest seeking its first win of the season after suffering consecutive home losses to the Arizona Cardinals and Las Vegas Raiders, both ending in 26-14 scores.
Chargers Hit Hard by Injuries
The Chargers face significant roster challenges, missing multiple key players due to injuries.
Defensive tackle Dalvin Tomlinson, defensive back Elijah Molden, and offensive linemen Trey Pipkins III and Kayode Awosika have been ruled out for the game.
Additionally, linebackers Denzel Perryman and center Tyler Biadasz remain on injured reserve, while tight ends David Njoku and Charlie Kolar are also sidelined.
The absence of Njoku and Kolar positions former Syracuse standout Oronde Gadsden as the primary tight end target for Los Angeles quarterback Justin Herbert.
In contrast, the Buffalo Bills enter the contest with momentum, averaging 38.5 points per game through their opening two victories.
Quarterback Josh Allen has compiled 582 passing yards and five touchdowns without throwing an interception, alongside four rushing touchdowns.
Buffalo's offense ranks second in total yards per game across the league while maintaining a zero-turnover record through two weeks.
Defensive tackle Ed Oliver returns to the lineup after missing last week's game against the Detroit Lions due to a hip injury, while running back Ty Johnson is set to make his season debut.
