So I just wanted to pound the zone tonight."
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Giants manager Tony Vitello praised the right-hander's competitive intensity and refusal to exit the game easily after throwing 105 pitches.
"I've still yet to shake his hand after that outing, which is kind of the norm after we pull a guy out of the game," said Vitello.
"If you'd have asked him to fistfight anybody on our team, even Ramos, he might have fist fought him to go back out there in the ninth inning.
So that is how competitive he is. If it gets directed in the wrong way, it can work against you.
But when he uses that fire to keep his house lit and warm instead of burning it down, he's capable of great things."
San Francisco's offense backed the pitching performance by scoring early against former Giants All-Star Kevin Gausman, who allowed seven runs in 5 1/3 innings.
Ramos led off the first inning with a triple and scored on a throwing error by Toronto shortstop Andrés Giménez.
Victor Bericoto contributed a two-run single in the sixth inning to knock Gausman out of the game before Ramos hit a three-run home run off reliever Tommy Nance.
Kazuma Okamoto hit a solo home run in the fifth inning for Toronto's lone run, ending a 29-inning scoreless drought for the Blue Jays.
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Giants right-hander Trevor McDonald is scheduled to pitch the second game of the series on Tuesday, while Toronto has not yet announced their starting pitcher.