Among the younger players, Italiano singled out Ilhan Fakili for his composure during the preseason, where the midfielder scored two goals.
Midtjylland arrives in Istanbul relying on striker Franculino, who returned to form in pre-season friendlies following a four-month knee and muscle injury recovery.
The Danish side, managed by Mike Tullberg, recently added defender Rasmus Nissen Kristensen to its squad, balancing the departure of winger Aral Simsir and the absence of injured forward Junior Brumado.
Besiktas team captain Orkun Kokcu confirmed that the squad quickly adapted to the new tactical requests and was fully focused on securing an advantage before traveling to Denmark.
"Everyone is 100% ready. The important thing is to get a good result tomorrow," said Kokcu.
The opening leg kicks off in Istanbul at 20:00 CET, with the return leg scheduled to take place in Denmark.
