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Mainoo established himself as a vital starter under Manchester United manager Michael Carrick, who took charge in January, and subsequently signed a new contract with the Red Devils in late April.
"Manchester United has always been my home; this special club means everything to my family," said Mainoo.
"I have grown up seeing the impact that our club has on our city, and I relish the responsibility that comes with wearing this shirt," he added.
"I have the privilege of living my dream every single day, with the same relentless desire to succeed here as when I joined my first training session at the age of six," Mainoo stated.
"We can all feel the momentum building inside the club.
I am determined to step up and play my role in helping Manchester United to regularly fight for major trophies in the years ahead," he concluded.
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Football365 reported that Manchester United is highly unlikely to sell Mainoo, given his status as a foundational player under Carrick's current project.
