He noted the World Cup follows a grueling club season where players often play three matches per week.
"Condition-wise, these players are unbreakable. It just doesn't look that way when they play Japan," Derksen clarified.
Derksen made an exception for Corinthians striker Memphis Depay, who lacks match rhythm while recovering from a thigh injury.
Statistical data showed Japan's aggressive pressing caused a visible drop in Dutch intensity, especially after manager Ronald Koeman substituted forwards Cody Gakpo, Donyell Malen, and Crysencio Summerville.
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The Netherlands dropped two points late in the game after initially leading 2-1. The squad faces Sweden on Saturday, a team that beat Tunisia in its opener.