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The veteran acknowledged the challenges of competing at this stage of his career.
"At this age and stage in my career, every day brings something new and unpredictable for me," Djokovic explained.
He expressed optimism about his upcoming schedule. "I'm hoping that I will come out at my best in a few days' time," Djokovic concluded.
Djokovic will next face Russian qualifier Roman Safiullin, who defeated 24th-seeded Brazilian João Fonseca 6-3, 6-3, 6-3.
Safiullin, ranked 132nd, wept on court as he recalled his recovery from a severe knee injury.
"After the U. S.
Open, I had to stop — for treating my injury," Safiullin said. "That time was super tough.
Even let's say half a year ago I didn't know if I will be able to be back."
Defending champion Jannik Sinner also advanced, beating American Jenson Brooksby 6-4, 6-3, 6-4.
Sinner hit 13 aces and won 87 percent of his first-serve points, achieving an Open era record of 20 consecutive third-round Grand Slam victories.
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Sinner will face Japanese qualifier Shintaro Mochizuki in the fourth round.