They'll be tough; they're a different type of opposition - and Matt Taylor's team at Exeter."
The fixture marks a quick return for striker Lorent Tolaj, who joined Bristol City from Plymouth for £4 million earlier this month after scoring 21 goals last season.
Skubala added, "There are no easy games in football, and we've seen that through pre-season; you see that with all the different results.
Newcastle will be saying that after what we've done tonight, so we just have to make sure, fingers crossed, we can get 90 and then come back from it healthy."
Plymouth's Perspective
Plymouth head coach Tom Cleverley welcomed the challenge of facing higher-tier opposition, saying, "We are expecting to see a similar side to the one that beat Newcastle 4-1.
Since Tolly has gone in there they have started scoring goals, which is no surprise."
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Cleverley expressed respect for Skubala and acknowledged the financial realities of modern football regarding Tolaj's departure, noting, "You feel for the supporters because you connect to a hero, an idol, and it can be short-lived."
He also highlighted Tolaj's potential, stating, "Just his determination alone to score goals is scary.
He has got a bright future, he has got a high ceiling and for the reasons you probably guess we want him to go and do well."
Plymouth will welcome back defenders Wes Harding, Julio Pleguezuelo, and Brendan Wiredu from injury, but captain Joe Edwards remains sidelined following knee surgery.
