The New York Yankees suffered their third consecutive loss on Monday, falling 5-3 to the Detroit Tigers at Comerica Park.
Ace Gerrit Cole had a rough outing, surrendering five runs and nine hits over 4 1/3 innings.
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It was Cole's first loss to Detroit since 2016.
Tigers starter Framber Valdez earned the win, allowing just one run on four hits while striking out eight over six innings.
New York tied the game 1-1 in the third inning when Ali Sanchez hit an RBI double, scoring Jose Caballero.
Caballero had walked and stolen second base.
Detroit took the lead in the bottom of the third.
Kevin McGonigle drove in Zack McKinstry, followed by consecutive two-out RBI singles from Spencer Torkelson and Colt Keith.
The Tigers extended their lead to 5-1 in the fourth and fifth innings.
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McGonigle hit an RBI double in the fourth, and Riley Greene launched a 422-foot solo home run in the fifth.
A brief seven-minute delay occurred in the fourth inning when an on-field camera mechanism emerged through the grass near second base.
The stadium grounds crew quickly resolved the issue.
New York attempted a comeback in the seventh inning.
Amed Rosario hit a two-run home run shortly after Sanchez left the game due to a pitch hitting his left wrist.
Detroit reliever Will Vest secured the final four outs to earn his second save of the season. The Yankees now hold a 46-31 record.
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The three-game series continues Tuesday night in Detroit. Yankees left-hander Carlos Rodon will face Tigers right-hander Casey Mize.