The 30-year-old Italian originally started the French Open ranked 105th before climbing back into the top 100, a position more reflective of his competitive history when healthy.
Injuries have frequently disrupted Berrettini's career momentum, drawing comparisons to physical struggles faced by other prominent tennis figures like Juan Martin del Potro throughout their professional tenures.
Despite these repetitive physical hurdles, Berrettini has established an exceptional reputation on grass courts, highlighted by his run to the prestigious Wimbledon singles final in 2021.
The Italian powerhouse has also claimed two titles at the Queen's Club tournament and previously reached the semifinal stages at both the Australian Open and the US Open.
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The first-round encounter at the All England Club marked the first head-to-head meeting between Wawrinka and Berrettini on the professional ATP circuit.
