"He doesn't really care," Rusedski added when asked about Zverev's potential preference for a final opponent.
Upcoming weather forecasts predict high temperatures for the second week of the tournament, which could impact Sinner's performance according to past trends discussed on the podcast.
"He's playing with house money at the moment because of the fact that he got his first major.
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Next week's supposed to be hot. We've talked about it.
Sinner does not like the heat," Rusedski commented.
If Djokovic reaches the final, the crowd is expected to heavily back the Serbian as he seeks an eighth Wimbledon title to equal Roger Federer's record.
"If Djokovic gets to the final, who's the crowd going to be for, Zverev or Djokovic? Most likely Djokovic because they'd want to see the 25th major.
They want to see him win his eighth Wimbledon title," Rusedski noted.
The high-stakes matchups scheduled to begin on Monday will determine who capitalizes on the open draw.
"So the second week starting on Monday all of a sudden gets really, really interesting. And this is where we separate the boys from the men," Rusedski stated.
Other players remaining in the section include Australia's Alex de Minaur, a seven-time major quarterfinalist who was forced to withdraw from a 2024 Wimbledon quarterfinal match against Djokovic due to a hip injury, alongside Italian star Flavio Cobolli and Kazakhstan's Alexander Bublik.
"But Zverev will be delighted. This is the best I've seen him play at Wimbledon.