Lam noted that several injured players are expected to return over the coming weeks, boosting squad depth. "From there, we're capable of doing anything.
We've got players coming back over the next couple of weeks, almost everyone should be back in contention," he said.
Friday's match is Leigh's last home game before temporary displacement while the pitch at Leigh Sports Village undergoes maintenance.
Lam stressed the importance of balancing the commercial excitement of the Las Vegas event with the immediate need for competition points.
"We do as good a job as anyone in the competition (of handling occasions), and we're going to be going there to win, no doubt about that," Lam said.
"We'll take some lessons from other people and I'll speak to as many as I can to make sure we're prepared."
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Hull FC Fielding Depleted Squad
Hull FC enters the match in a dire situation, missing 15 players due to injuries and suspensions, including Will Pryce, Jed Cartwright, John Asiata, and the suspended Yusuf Aydin.
Interim coach Simon Last has made seven changes to the squad that faced Bradford last weekend, introducing academy products Ben Johnson and Lennon Clark for potential first-team debuts.
"Lots of energy, lots of enthusiasm.
If they get the opportunity to make their debut, it'll be a special occasion for them," Last said.
He added that promoting local academy players who grew up supporting the club helps galvanize the senior members during the injury crisis.
