"They are big Black and White fans, and their families are big Black and White fans, and they've earned their opportunity.
They have come through the system and they will be very grateful to the Hull Wyke club for helping them on this journey," Last said.
The selection changes mean veteran winger Tom Briscoe will play his 200th game for Hull FC.
Winger Harvey Barron is also set for his second game back from injury, aiming to regain his best form.
"I just want to get back playing consistently and playing to a good standard.
I thought the back end of last year was probably some of the best rugby I've been playing.
I'm just hoping to get back to that standard and help contribute to the team," Barron said.
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Veteran forward Herman Ese'ese remains sidelined as the coaching staff avoid rushing him back from a severe Achilles injury.
